SYMPOSIUM 1997 LECTURE PROGRAMME:

Chair: Prof Frank McCapra

Monday 22 September 1997

Time	Lecture (or other activity)
0830-0930: Registration at the Babbage Lecture Theatre
0930-0950 Invited speaker (CV)	Prof Frank McCapra (CV) University of Sussex Curiosity has its Rewards - An Outline of Industrial Applications of Chemiluminescence (Abstract)
0950-1020 Invited speaker (CV)	Prof Larry Kricka (CV) Hospital of the University of Pennsylvania, USA Prospects for Chemi- and Bioluminescent Immunoassays and Probe Assays in the Food and Pharmaceutical Industries (Abstract)
1020-1035	I Bronstein, C Olesen, J Mosier, and JC Voyta Tropix, Inc., Bedford, MA 01730, USA Chemiluminescent Detection of Proteins and DNA Probes (Abstract)
1035-1050	David F Smith SeaLite Sciences, Norcross, GA, USA A Non-Enzymatic, Bioluminescent Detection System For Quantitative Analysis of Nucleic Acids (Abstract)
1050-1130: Morning tea and coffee in the Exhibition Room
1130-1200 Invited speaker (CV)	Dr Keith Wood (CV) Promega Corporation, Madison, Wisconsin, USA Applications of Bioluminescence for Rapid Screening and Analysis of Gene Expression and Cell Viability (Abstract)
1200-1215	MD Cunningham(1), SM Cunningham(2), L Zhu(2) and S Kain(2) (1) Molecular Devices Corporation, 1311 Orleans Drive, Sunnyvale, CA 94089, USA; (2) CLONTECH Laboratories Inc, 1020 East Meadow Circle, Palo Alto, CA 94303, USA Fluorometric Imaging Plate Reader (FLIPR) Analysis of the Induction of eGFP and Luciferase Under the Control of a Regulatable Genetic Switch (Abstract)
1215-1230	Claire Elcock, Simon Hill and Ian J Chetland Xenova Limited, Slough, Berkshire, UK Applications of Luminescent Technology in High Throughput Screening (Abstract)
1230-1245	Chris Roelant (1)*, Sue Brown (2), Jenny Stables (2), Stephen Rees (2), Dave Burns (3) (1) RTRT, Leuven, Belgium; (2) Receptor Systems, Glaxo Wellcome Research and Development, Stevenage, UK The Development of a Dual Glow-Signal Firefly and Renilla Luciferase Assay for High Throughput Compound Screening (Abstract)
1245-1300	Ineabel Horneij, Kelli Feather-Henigan, Paul D Davis and Kimberly K Hines Pierce Chemical, 3747 N. Meridian Rd. Rockford, IL 61101, USA A Unique Chemiluminescent Substrate for High Throughput Screening Applications (Abstract)
1300-1415: Lunch at Pembroke College
1415-1445 Invited speaker (CV)	Dr Martin Easter (CV) Celsis-Lumac Ltd, UK Industrial Implementation of Bioluminescence Assays for the Assessment of Microbiological Safety and Quality - Applications and Issues (Abstract)
1445-1500	Veikko Tarkkanen ConCell BV, Nettetal, Germany Determination of Organic Disinfectants by Means of Chemiluminescence (Abstract)
1500-1515	E D'Haese (1), HJ Nelis (1) and W Reybroeck (2) (1) University of Ghent, Laboratory for Pharmaceutical Microbiology, Harelbekestraat 72, B-9000 Ghent, Belgium; (2) Government Dairy Research Station, Agricultural Research Centre Ghent, Brusselsesteenweg 370, B-9090 Melle, Belgium Development and Evaluation of a Chemiluminometric Screening Assay for the Detection of Tetracycline Residues in Milk (Abstract)
1515-1530	S Dellar and MK Turner The Advanced Centre for Biochemical Engineering, Department of Biochemical and Chemical Engineering, University College London, Torrington Place, London WC1W 7JE, UK Improving the Stability of Firefly Luciferase by Medium Engineering (Abstract)
1530-1615: Afternoon tea/coffee in the Exhibition Room
1615-1645 Invited speaker (CV)	Mr Brian McCarthy (CV) Executive Manager, British Textiles Technology Group (BTTG) Shirley, Manchester, UK Bioluminescent Protocols for the Evaluation of Medical Barrier Performance (Abstract)
1645-1700	Arne Lundin BioThema, Strandvägen 36, S-130 54 Dalarö, Sweden Kinetic Properties of ATP Reagents as Influenced by Luciferase Level (Abstract)
1700-1730 Invited speaker (webpage)	Prof Anthony Campbell (webpage) University of Wales College of Medicine, Cardiff, Wales Lighting up the Chemistry of Living Cells: Commercial Potential and Applications (Abstract)
Evening Reception at Christ's College, Cambridge

Tuesday 23 September 1997

Time	Lecture (or other activity)
0845-0915 Invited speaker (CV)	Prof Aladar Szalay (CV) Center for Molecular Biology & Gene Therapy, Loma Linda University, California, USA Light Based Detection of Pathogenic Bacteria in Vivo in Infected Hosts: a Novel Assay System with Industrial Potential (Abstract)
0915-0945 Invited speaker (CV)	Prof Aldo Roda (CV) Dept of Pharmaceutical Sciences, University of Bologna, Italy Ultrasensitive Bio- and Chemiluminescent Imaging Using an Optical Microscope-Videocamera Luminograph; Applications in Biosciences and Drug Screening (Abstract)
0945-1000	Peter Andreotti and Fritz Berthold Zylux Corporation, Boca Raton, Florida, USA Applications of a New High Sensitivity Luminometer in Industrial Microbiology (Abstract)
1000-1015	RJ Ellis and AG Wright Electron Tubes Ltd, Ruislip, UK Optimal use of Photomultipliers for Chemiluminescent and Bioluminecent Applications (Abstract)
1015-1115: Morning tea/coffee in Exhibition Room
1115-1145 Invited speaker (CV/website)	Prof Gordon Stewart Dept of Applied Biochemistry & Food Science, University of Nottingham, UK The Light and Dark of Bacterial Life and Death: Not Just Bacterial Detection But New Insights into Inimical Processes (Abstract)
1145-1215	Dr Sandy Primrose Azur Environmental Ltd, Wokingham, UK Luminescence-Based Testing for Mutagens (Abstract)
1215-1230	Gary Thorpe Wolfson Applied Technology Laboratory, Queen Elizabeth Medical Centre, Edgbaston, Birmingham B15 2TH, UK Rapid Pollution Tracing and Water Quality Testing Using Enhanced Chemiluminescence (Abstract)
1230-1245	Robert G Hood F.S.M. Technologies Ltd, Clydebank Business Park, Clydebank G81 2NT, UK Advanced Membrane Systems for Luminescence Assays (Abstract)
1245-1415: Lunch at Pembroke College
1415-1445 Invited speaker (CV)	Dr Richard Massey (CV) IGEN International, Inc, Gaithersburg, Maryland, USA Electrochemiluminescence - Based Assays. An Overview of Applications for the Food, Water and Pharmaceutical Industries (Abstract)
1445-1500	AP Schaap* and H Akhavan-Tafti Lumigen, Inc., Southfield, MI 48034, USA The Development of Chemiluminescent Phosphatase and Peroxidase Substrates for High Throughput Screening (Abstract)
1500-1515	J Cryer (1), JP Aston (2), I Weeks (1) and JS Woodhead (1) (1) Molecular Light Technology Research Ltd, (2) Shell International Chemicals in association with Molecular Light Technology Research Ltd, Cardiff Business Technology Centre, Senghenydd Road, Cardiff CF2 4AY, UK Industrial Applications of Chemiluminescent Immunoassays for Haptens (Abstract)
1515-1530	Alex A Waldro, III, Jonathan Fellers, Sarah Hammond, and Calvin PH Vary Maine Medical Center Research Institute, South Portland, ME 04106, USA Novel Glow Chemiluminescent Compounds for Detection of Hydrogen Peroxide (Abstract)
1530-1545	Closing Remarks: Prof Frank McCapra (CV)
1545-1615: Afternoon tea/coffee

POSTERS
These were displayed in the Small Examination Hall from 0830 Monday and then throughout the symposium

E. Broens (1), A Masolijn (1), F Martens (1), A Smith (1), P Dawson (2), S Richardson (2), M Pfaffli (3)
(1) Perstorp Analytical, Landgraaf, The Netherlands; (2) Ashby Dairy Co., Ashby-de-la-Zouch, UK; (3) Intermilch AG, Bern, Switzerland
Rapid Method for the Detection of Post-Pasteurisation Contamination in Pasteurised Milk
(Abstract)

SPM Crouch (1), DA Bradbury (1), TD Teft (1), A Batchelor (2), and KJ Slater (3)
(1) The David Evans Medical Research Centre, Nottingham City Hospital NHS Trust, UK; (2) Labtech International, East Sussex, UK; (3) LumiTech Ltd, Nottingham UK
A Rapid, Safe, High Throughput Screening Method for Detection of Cell Cytotoxicity
(Abstract)

CA Davidson, CJ Griffith and LM Fielding
Food Safety Research Group, University of Wales Institute, Colchester Avenue, Cardiff CF3 7XR, UK
ATP Bioluminescence and the Validation and Monitoring of Cleaning Programmes
(Abstract)

S Dellar, MK Turner
The Advanced Centre for Biochemical Engineering, Department of Biochemical and Chemical Engineering, University College London, Torrington Place, London WC1W 7JE, UK
Modification of the Bioluminescence Activity of Firefly Luciferase by Selective Inhibition
(Abstract)

A Hearn, L Gerdes, P Meighan, H Woods, D Ferguson
Celsis-Lumac, Cambridge, UK
Detection and Enumeration of Bacteria Within Six Hours Using the Celsis digital™ Bioluminescence Detection Syste
(Abstract)

S Hill (1), C Elcock (1), D MacAllen (1), S Temple (2) and Diana C Hill (1)
(1) Xenova Ltd., Slough, UK; (2) Packard Instrument Company, Pangbourne, UK.
A Novel Assay for Determining Cytotoxicity and Reporter Gene Expression Using H33258 and LucLite™
(Abstract)

Erik Joly (1)*, Mireille Caron (1), Claire Normand (1), Luc Menard (1), Dave Burns (2) and Hans Pirard (2)
(1) BioSignal Inc., Montreal (Quebec), Canada; ( ) 2Packard Instrument Company, Meriden, CT, USA;
The Use of CytoGem™ GFP Reporter Vectors for Mapping Promoter and Enhancer Elements in Microplates
(Abstract)

T Jung (1), G Schabert (2) and S Stürzer (2)
(1) BIOSYNTH International Inc., Naperville, IL, USA; (2) BIOSYNTH AG, Staad, Switzerland.
Coelenterazine: Bioluminescent Ca++ Indicator and Renilla Luciferase Substrate
(Abstract)

Dennis Klenk, Dean Savage, Laura Sykaluk and Ruiyin Chu
Pierce Chemical Company, 3747 N. Meridian Rd. Rockford, IL 61105, USA
INDIA™ HisProbe™-HRP Gives Enhanced Detection Specificity for Polyhistidine-Tagged Fusion Proteins and Allows for High Detection Sensitivity with SuperSignal® Chemiluminescent Substrate
(Abstract)

Jan Knight
Knight Scientific Ltd, 18 Western College Road, Plymouth PL4 7AG, UK
Pholasin® Assays for Blood Biocompatibility Monitoring
(Abstract)

Jorma Lampinen (1), Juha Lappalainen (2)
(1) Bio-Orbit Oy, Turku, Finland; (2) Bio-Nobile Oy, Turku, Finland.
Inhibitory Effect of Disinfectants on Luminescent ATP Measurement
(Abstract)

K Morwood (1), E Abley (1), J Kay (1), T Ling (1), R Johnson (1), H Morris (2)
(1) SmithKline Beecham Consumer Healthcare, Maidenhead, UK; (2) Celsis-Lumac, Cambridge, UK
The Use of ATP Bioluminescence Technology for the Detection of Microbial Contamination in Personal Care Products
(Abstract)

Ângela R Ribeiro (1), Célia M Antunes (1), Luís M Rosário (1,2) and Maria H Gil (3)
(1) Center for Neuroscience and Cell Biology, University of Coimbra, Portugal; (2) Department of Biochemistry, FCTUC, P.O. Box 3126, 3000 Coimbra, Portugal; (3) Department of Chemical Engineering, FCTUC, Coimbra, Portugal
Immobilisation of Firefly Luciferase on Glass Strips as an Alternative Strategy for Luminescent Detection of ATP
(Abstract)

Chris Roelant (1), Al Kolb (2), Dave Burns (3)
(1) RTRT, Leuven, Belgium; (2) Packard Instrument Company, Meriden, CT, USA, (3) Packard Instrument Company, Meriden, CT, USA
The Use of Constant-Quanta™ Luminescent Reagents for High Throughput Screening in 96- and 384-well Microplates
(Abstract)

G Sarlet (1), R Renotte (1), G Ghitti (1), JL Cloux (1), R Lejeune (2)
(1) Biocode Biotechnology, 4000-Liège, Belgium; (2) Pharmacy Institute, Analytical Chemistry Department, Liège University, Belgium
Novel Chemiluminescent Probe as Efficient label for Hydroxyls in Biomolecules
(Abstract)

Jenny Stables, Steve Rees, Elaine Murrison, Melanie Lee
Receptor Systems Unit, GlaxoWellcome Research and Development, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK
Aequorin-Expressing Mammalian Cell Lines Used to Characterise Oxytocin and Vasopressin Receptor Pharmacology
(Abstract)

HG Wada (1), IL Dale (2), EM Tucker (2), CJ Oakley (2), BD Neagle (2), KS Schroeder (1), M Sullivan (2) and E Sullivan (2)
(1) Molecular Device Corporation, 1311 Orleans Drive, Sunnyvale, CA, USA, (2) Astra Charnwood, Bakewell Road, Loughborough,UK
Measurement of Firefly and Renilla Luciferase in the FLIPR
(Abstract)

Gijsbert Zomer, Marjorie Jacquemijns
National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Novel Acridane Esters as Efficient Chemiluminescence Substrates for the Detection of Horseradish Peroxidase Immunoassay Applications
(Abstract)

Exhibitors

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